Better Together: The Power of Omega-3 Fish Oil & CoQ10


By Harley Stabler
4 min read

Better Together: The Power of Omega-3 Fish Oil & CoQ10

The Second Entry in Our ‘Powerful Pairs’ Series

Following our first blog on Prebiotics and Probiotics, we continue our exploration of supplement synergies with another powerhouse combination: Omega-3 Fish Oil and CoQ10. This duo is particularly well-suited for our cardiovascular health, working together to reduce inflammation, support cellular energy production, and enhance overall heart function.

While Omega-3 fatty acids are renowned for their ability to lower triglycerides and support brain health, CoQ10 is a vital nutrient for energy production in our cells, particularly within the heart. Together, they form a complementary pair that offers a wide range of benefits beyond heart health, including cognitive support and anti-ageing effects.

 

Why Omega-3 and CoQ10 Work So Well Together

Cardiovascular disease remains one of the leading health concerns globally. Many people turn to Omega-3 Fish Oil for its well-documented ability to lower blood pressure, support healthy cholesterol levels, and reduce inflammation (Mozaffarian & Wu, 2011). Meanwhile, CoQ10 plays a crucial role in our mitochondrial energy production, ensuring the heart has the fuel it needs to function effectively (Rabanal-Ruiz et al., 2021).

However, what makes this pairing particularly powerful is their combined effect on reducing oxidative stress and improving mitochondrial efficiency. Omega-3s improve circulation and reduce inflammation, while CoQ10 enhances cellular energy, particularly in the heart muscle. Together, they form a holistic approach to cardiovascular and metabolic health.

 

What Are Omega-3 Fatty Acids?

Omega-3 fatty acids are essential for our health, but our bodies cannot produce them efficiently, so they must come from our diet or supplementation. They are particularly beneficial for heart, brain, and joint health due to their anti-inflammatory and cardiovascular-supportive properties.

The three main types of Omega-3s include: EPA (Eicosapentaenoic Acid), which helps reduce inflammation and supports cardiovascular function; DHA (Docosahexaenoic Acid), which is vital for brain function and cognitive health; and ALA (Alpha-Linolenic Acid), a plant-based Omega-3 that can be converted into EPA and DHA, though inefficiently.

Some of the best dietary sources of Omega-3s include fatty fish (salmon, mackerel, sardines), chia seeds and flaxseeds, walnuts, and algal oil (a vegetarian source of DHA). We need to ensure we try to regularly lean towards these foods. 

 

What is CoQ10?

Coenzyme Q10 (CoQ10) is a fat-soluble antioxidant found in nearly every cell in our body, with particularly high concentrations in the heart, liver, and kidneys. It is essential for ATP (energy) production, which fuels our cells and supports organ function.

However, as we age, CoQ10 levels decline, leading to decreased energy production and increased oxidative stress (Littarru & Tiano, 2010). This can contribute to fatigue, muscle weakness, and cardiovascular issues.

Some of the best dietary sources of CoQ10 include fatty fish (tuna, salmon), organ meats (heart, liver), nuts and seeds, and spinach and broccoli.

 

How Omega-3 and CoQ10 Complement Each Other

Scientific research highlights several key ways in which these two nutrients work better together. These include:

  • Enhanced Heart Function: Omega-3s reduce arterial inflammation, while CoQ10 ensures that the heart muscle has the energy it needs to pump efficiently (Mori et al., 2009).
  • Improved Cellular Energy Production: CoQ10 is crucial for mitochondrial ATP production, and Omega-3s help maintain mitochondrial integrity (Zozina et al., 2018).
  • Greater Antioxidant Protection: CoQ10 enhances the antioxidant properties of Omega-3s, reducing oxidative stress, a major contributor to cardiovascular disease (Mozaffarian & Wu, 2011).

 

Doctor’s Best and Nordic Naturals: Premium Choices for Omega-3 and CoQ10

If you're looking for high-quality supplementation, Doctor’s Best and Nordic Naturals are trusted brands known for their purity, potency, and scientific backing. Their formulations prioritise effectiveness while ensuring safety from harmful contaminants.

For those looking to supplement with Omega-3 and CoQ10, we recommend:

By choosing Doctor’s Best and Nordic Naturals, you are investing in a premium, research-backed approach to heart and metabolic health.

 

How to Take Omega-3 and CoQ10 Together

To maximise the benefits of this combination, there are three simple rules we need to understand. These are:

  1. Take them with meals containing healthy fats. Both Omega-3s and CoQ10 are fat-soluble, meaning they absorb better when consumed with dietary fat.
  2. Consistency is key; regular supplementation provides long-term cardiovascular and anti-inflammatory benefits
  3. Choose high-quality sources and opt for purified fish oil and bioavailable CoQ10 to ensure efficacy.

 

Conclusion: A Heart-Healthy Combination

The combination of Omega-3 Fish Oil and CoQ10 offers us comprehensive support for our heart health, energy production, and inflammation reduction. These two essential nutrients work in harmony, creating a foundation for cardiovascular wellness and overall vitality.

Doctor’s Best and Nordic Naturals provide us with high-quality, scientifically validated supplements to help us optimise our health and longevity.

Take control of your heart health by incorporating Omega-3s and CoQ10 into your routine, and experience the benefits firsthand.


  • Mori, T. A., Burke, V., Puddey, I., Irish, A., Cowpland, C. A., Beilin, L., Dogra, G., & Watts, G. (2009). The effects of ω3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: A randomized controlled trial. Journal of Hypertension, 27(9), 1863-1872.  
  • Littarru, G. P., & Tiano, L. (2010). Clinical aspects of coenzyme Q10: an update. Nutrition (Burbank, Los Angeles County, Calif.), 26(3), 250–254. 
  • Mozaffarian, D., & Wu, J. H. (2011). Omega-3 fatty acids and cardiovascular disease: Effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047-2067. 
  • Rabanal-Ruiz, Y., Llanos-González, E., & Alcain, F. J. (2021). The Use of Coenzyme Q10 in Cardiovascular Diseases. Antioxidants, 10(5), 755 
  • Zozina, V. I., Covalova, O. A., & Kostin, A. V. (2018). Coenzyme Q10 in cardiovascular and neurological diseases. Journal of Clinical Medicine, 7(7), 233. 

This article provides informational advice and is not a substitute for medical care. Curated by experts for accuracy, we take great care to ensure the information is up-to-date and relevant. However, you should always consult your GP or healthcare professional before using supplements or alternative products, particularly if you have medical conditions or are under supervision.


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